The opener for Stanley came after just 8 minutes when summer signing from Altrincham Ian Craney powered a magnificent goal past the home 'keeper to send the traveling fans wild.
On 33 minutes Robbie Williams doubled the lead with a powerful header after Steve Jagielka, another summer recruit, crossed a suberb ball into the area.
Home captain Jim Bently headed home Kieron Walmsley's cross but the final score saw Accrington Stanley desevedly take the 3 points home.
Morecambe: Sollitt, Walmsley, Bentley, Swan, Howard, Thompson, Blackburn, McFlynn (Stringfellow 69), Curtis, Twiss (Hunter 65), O'Connor (Carlton 45). Subs Not Used: Rogan, Gregoire.
Goals: Bentley 78.
Accrington Stanley: Kennedy, Cavanagh, Halford, Bimson, Williams, Jagielka, McEvilly (Howson 70), Brannan, Craney, James (Cook 81), Mullin. Subs Not Used: Howarth, Banim, Alcock.
Booked: James, Cook, Brannan.
Goals: Craney 8, Williams 35.
Att: 2,393.
Ref: R Pollock (Merseyside).