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A double from ex-Liverpool striker Neil Mellor got the ball rolling for Preston's very strong Reserve outfit.
Patrik Agyemang, Mainwearing and Soley scored the other goals for North End, with Mawene completing sixty five minutes of football following a 'disasterous' injury last season.
Leighton McGivern grabbed the Stanley consolation in the 50th minute.
Andy Todd, who has been in magnificent form for the first team of late also appeared in the game.